We've used this site along with expedia, kayak, and travelocity. There are times when the prices and routes are better on this website compared to the competition as well as going directly on the airline's website or going through a travel agent. We've mainly used this site when traveling internationally. Somehow, they've been the ones to offer the better fares for those routes. It just depends. Either way, we are pleased with orbitz.com.
I have been a fan of Orbitz for several years now and have planned many vacations on it. It definitely shows the most current prices and many prices depending on the search. The best thing about it that it doesn't open all the windows for what you search for rather a dashboard.